Adenine nucleotide translocase (ANT) is a mitochondrial protein that plays a crucial role in the transport of ATP and ADP across the inner mitochondrial membrane. This transport process is essential for maintaining cellular energy balance and metabolic regulation. ANT is responsible for exchanging ATP produced in the mitochondrial matrix with ADP produced in the cytosol, allowing for the efficient production of cellular energy through oxidative phosphorylation. Dysfunction of ANT has been implicated in various human diseases, including cardiac disorders and neurodegenerative diseases. Studying the structure and function of ANT can provide valuable insights into mitochondrial function and uncover potential therapeutic targets for these diseases.